Multiplex lateral-flow test strips fabricated by two-dimensional shaping.

Rapid assay format for multiplex detection of humoral immune responses to infectious disease pathogens (HIV, HCV, and TB).

A novel assay is described for multiplex detection of antibodies against different pathogens from a single sample. The assay employs a modified lateral flow format (consecutive flow, CF) together with a sensitive reporter particle technology (up-converting phosphor technology, UPT) that allows for fully instrumented assay analysis. Lateral flow (LF) strips developed for the detection of human a...

Preliminary Development of a Magnetically Assisted Test Strip (MATS) Cartridge and Fluorescent DNA Aptamer-Magnetic Bead Quantum Dot Sandwich Assays for Multiplexed Food Safety Applications

Preliminary development of a simple mesofluidic multi-channel plastic cartridge with underlying external magnet to drag DNA aptamer-coated paramagnetic beads through fluids in the channels while developing a sandwich assay with quantum dot-conjugated reporter aptamers is described. This approach is superior to traditional lateral flow test strips in several ways including: 1) the ability to con...

Secondary flows over artificial bed strips

Characteristics of open channel flows can be significantly modified in the presence of secondary flows. In this study, cellular secondary flows were artificially generated with alternate rough and smooth bed strips, which were aligned longitudinally in an open channel. Flow measurements were conducted with a two-dimensional Laser Doppler Anemometer system. Experimental results show that the dis...

Rapid Lateral Flow Test Strips

Dual Recognition Element Lateral Flow Assay Toward Multiplex Strain Specific Influenza Virus Detection

Different influenza virus strains have caused a number of recent outbreaks killing scores of people and causing significant losses in animal farming. Simple, rapid, sensitive, and specific detection of particular strains, such as a pandemic strain versus a previous seasonal influenza, plays a crucial role in the monitoring, controlling, and management of outbreaks. In this paper we describe a d...